At least two people were killed and many others injured on Saturday during a shooting at a night club in Lancaster, South Carolina, police said.

The police said in a statement that they were investigating the incident which occurred at around 2:45 AM local time.

Those killed in the shooting are reported to be adult males. Four of those injured were airlifted to medical facilities for treatment, while others were taken to local facilities.

“This was a violent incident of huge magnitude that was witnessed by lots of people,” Lancaster County Sheriff Barry Faile said in a statement. “Two people are dead, and many more are seriously injured. The shooter or shooters are out there. We need to talk with everybody who was at the club when the shooting happened, and I encourage those witnesses to contact us immediately so those responsible for these deaths and injuries can be taken into custody.”

The statement said that a large crowd had gathered at the night club when the shooting occurred, and that shots were fired both inside and outside the bar.

The U.S. has witnessed numerous gun attacks in 2019, with over 280 cases recorded.

The figures have sparked a debate on gun laws in the country, with some public figures calling for stricter regulations to be put in place.